Title of article
Synthesis and cytotoxicity of 2α-amido docetaxel analogues
Author/Authors
Wei-Shuo Fang، نويسنده , , Ying Liu، نويسنده , , Hongyan Liu، نويسنده , , Shaofeng Xu، نويسنده , , Liang Wang، نويسنده , , Qi-Cheng Fang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
1543
To page
1546
Abstract
Various 2-amido docetaxel analogues were prepared and evaluated for their cytotoxicities. Among them, m-methoxy and m-chlorobenzoylamido analogues were most active but not superior to docetaxel and paclitaxel, and -seco analogues inactive. Change of 2-benzoate to 2-benzamide may not improve their activities to drug-resistant cell lines.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792256
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