Title of article
Synthesis and biological activity of polygalloyl-dendrimers as stable tannic acid mimics
Author/Authors
S. Bart A. Halkes، نويسنده , , Ioannis Vrasidas، نويسنده , , Gilbert R. Rooijer، نويسنده , , Albert J. J. van den Berg، نويسنده , , Rob M. J. Liskamp، نويسنده , , Roland J. Pieters، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
1567
To page
1570
Abstract
Inspired by the structure of tannic acid, first- to third-generation dendrimers containing two, four, and eight galloyl moieties were synthesized. Stability, antioxidant activity and collagen cross-linking activity of the natural product and its dendrimer analogues were compared. The experimental results indicate that polygalloyl dendrimers might be used as new lead compounds to improve the long-term healing characteristics of burn wounds.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792261
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