Title of article
Synthesis and bioactivities of novel 4,5,6,7-Tetrahydrothieno[2,3-c]pyridines as inhibitors of tumor necrosis factor-α (TNF-α) production
Author/Authors
Masakazu Fujita، نويسنده , , Taketsugu Seki، نويسنده , , Haruaki Inada، نويسنده , , Naoko Ikeda، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
5
From page
1607
To page
1611
Abstract
Novel 4,5,6,7-tetrahydrothieno[2,3-c]pyridine derivatives were synthesized and evaluated for their abilities to inhibit lipopolysaccharide (LPS)-stimulated production of TNF-α in rat whole blood. Several of these compounds exhibited potent inhibitory activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792271
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