• Title of article

    A new lipophilic fluorescent probe for interaction studies of bioactive lipopeptides with membrane models

  • Author/Authors

    Elisa Peroni، نويسنده , , Gabriella Caminati، نويسنده , , Piero Baglioni، نويسنده , , Francesca Nuti، نويسنده , , Mario Chelli، نويسنده , , Anna M. Papini، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    1731
  • To page
    1734
  • Abstract
    The new fluorescent lipophilic moiety 11-[(7-amino-4-methyl-2-oxo-2H-1-benzopyran-3-acetyl)amino]undecanoic acid (AMCA-ωAud-OH) was introduced by SPPS at the N-terminus of the immunodominant epitope GpMBP(74–85). FRET experiments using the new fluorescent lipopeptide demonstrate that the peptide interacts with much more affinity with the membrane compared to the lipid free analogue.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2002
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    792300