Solid-phase C–C and C–O bond forming reactions using ‘Traceless’ π-arene–chromium linkers

The scope of solid-phase reactions utilizing a ‘traceless’ π-arene–chromium linker has been expanded to include the addition of organo-lithium reagents to a supported ester group, generation and alkylation of an enolate anion, and substitution via the Mitsunobu reaction. Immobilization of ortho-disubstituted polyfunctionalized arene chromium dicarbonyl species onto the solid support and subsequent, selective transformation is also reported.