• Title of article

    Oligonucleotides containing 7-vinyl-7-deazaguanine as a facile strategy for expanding the functional diversity of DNA

  • Author/Authors

    Akimitsu Okamoto، نويسنده , , Toshiji Taiji، نويسنده , , Kazuki Tainaka، نويسنده , , Isao Saito، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    2
  • From page
    1895
  • To page
    1896
  • Abstract
    A modified nucleobase 7-vinyl-7-deazaguanine (VG) produced adducts with maleimides through Diels–Alder cycloaddition under very mild conditions. By this method, post-synthetic modification to oligonucleotides with diverse functionality (carboxylic acid, pyrene, benzophenone, succinimidyl ester, nitroxide and biotin) was accomplished.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2002
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    792336