Inhibition of feline immunodeficiency virus (FIV) replication by DNA binding polyamides
Author/Authors :
Sanjay K. Sharma، نويسنده , , Jean-Noel Billaud، نويسنده , , Manju Tandon، نويسنده , , Olivier Billet، نويسنده , , Byong-Sam Choi، نويسنده , , Mary L. Kopka، نويسنده , , Tom R. Phillips، نويسنده , , J. William Lown، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Pages :
4
From page :
2007
To page :
2010
Abstract :
Two DNA minor-groove binding polyamides 1 and 2 were designed and synthesized and evaluated for inhibition of FIV-34TF10 replication. Both 1 and 2 decreased the replication of FIV-34TF10 by 75% by acting at the level of the virus but outside of the LTR or env region.
