Title of article :
Thiourea-based gemfibrozil analogues as HDL-elevating agents
Author/Authors :
Gary M. Coppola، نويسنده , , Robert E. Damon، نويسنده , , J. Bruce Eskesen، نويسنده , , Dennis S. France، نويسنده , , James R. Paterniti Jr.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
A series of gemfibrozil analogues with a thiourea moiety embedded in the side chain was prepared and evaluated as HDL-elevating agents. Derivatives 8b, 9b, 9c, and 9d were found to be approximately as effective as gemfibrozil (1) for HDL cholesterol elevation.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
