Author/Authors :
Haripada Khatuya، نويسنده , , Richard H. Hutchings، نويسنده , , Gee-Hong Kuo، نويسنده , , Virginia L. Pulito، نويسنده , , Linda K. Jolliffe، نويسنده , , Xiaobing Li، نويسنده , , William V. Murray، نويسنده ,
Abstract :
Antagonists of the α1-adrenergic receptors (α1-ARs) are useful for the treatment of benign prostatic hyperplasia. A series of potent and subtype-selective α1a-AR antagonists has been synthesized, displaying in vitro binding affinity in the low the nanomolar range.
