Title of article
4-Aminoquinolines as a novel class of NR1/2B subtype selective NMDA receptor antagonists
Author/Authors
Emmanuel Pinard، نويسنده , , Alexander Alanine، نويسنده , , Anne Bourson، نويسنده , , Bernd Büttelmann، نويسنده , , Marie-Paule Heitz، نويسنده , , Vincent Mutel Ramanjit Gill، نويسنده , , Gerhard Trube، نويسنده , , René Wyler، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
5
From page
2615
To page
2619
Abstract
Screening of the Roche compound library led to the identification of 4-aminoquinoline 4 as structurally novel NR1/2B subtype selective NMDA receptor antagonist. The SAR which was developed in this series resulted in the discovery of highly potent and in vivo active blockers.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792508
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