Title of article
The first synthesis and antifungal activities of 9-methoxystrobilurin-type β-substituted β-Methoxyacrylate
Author/Authors
Hiromi Uchiro، نويسنده , , Koh Nagasawa، نويسنده , , Tomoya Kotake، نويسنده , , Daiju Hasegawa، نويسنده , , Aya Tomita، نويسنده , , Susumu Kobayashi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
2821
To page
2824
Abstract
The first synthesis of 9-methoxystrobilurin-type β-substituted MOAs was successfully achieved. A chiral oudemansin-type β-substituted MOA was also synthesized utilizing Mukaiyamaʹs asymmetric aldol reaction. Antifungal activities of the synthesized compounds against several representative fungi were examined by disk-diffusion assay. As a result, unique and superior antifungal properties of 9-methoxystrobilurin-type β-substituted MOAs compared with those of oudemansin-type analogue were clearly revealed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792549
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