Title of article
Design, synthesis and evaluation of 4-imidazolylflavans as new leads for aromatase inhibition
Author/Authors
Christelle Pouget، نويسنده , , Catherine Fagnere، نويسنده , , Jean-Philippe Basly، نويسنده , , Gerard Habrioux، نويسنده , , Albert-José Chulia، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
2859
To page
2861
Abstract
Two 4-imidazolylflavans were synthesized and their relative stereochemistry was established by 1H and 13C NMR data. These compounds were tested for their activity to inhibit aromatase. It was observed that the introduction of an imidazolyl group at carbon 4 on flavan nucleus led to potent molecules.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792558
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