Title of article
Novel nucleotide phosphonate analogues with potent antitumor activity
Author/Authors
Monica Bubenik، نويسنده , , Rabindra Rej، نويسنده , , Nghe Nguyen-Ba، نويسنده , , Giorgio Attardo، نويسنده , , France Ouellet، نويسنده , , Laval Chan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
3063
To page
3066
Abstract
We have identified several nucleotide phosphonates demonstrating in vitro antiproliferative activity in several human cancer cell lines with IC50 values in the μM range. The synthesis as well as structure–activity relationship are described.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792600
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