Synthesis and structure–activity relationships of aminoalkylazetidines as ORL1 receptor ligands
Author/Authors :
Wen-Lian Wu، نويسنده , , Mary Ann Caplen، نويسنده , , Martin S. Domalski، نويسنده , , Hongtao Zhang، نويسنده , , Ahmad Fawzi، نويسنده , , Duane A. Burnett، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Pages :
4
From page :
3157
To page :
3160
Abstract :
A series of aminoalkylazetidines has been discovered as novel ORL1 receptor ligands. Structure–activity relationships have been investigated at the azetidine N and the alkyl side chain sites. Several potent and selective analogues have been identified.
