Title of article :
Benzotrithiole 2-oxide: A new family of thiol-Activated DNA-Cleaving functionalities
Author/Authors :
Alex H. F. Lee، نويسنده , , Albert S. C. Chan، نويسنده , , Tianhu Li، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
It was demonstrated in our studies that benzotrithiole 2-oxide was capable of causing efficient DNA cleavage in the presence of 2-mercaptoethanol or glutathione and exhibited potent cytotoxic properties against certain cancer cell lines.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
