• Title of article

    Prodrug and covalent linker strategies for the solubilization of dual-Action antioxidants/Iron chelators

  • Author/Authors

    David Bebbington، نويسنده , , Claire E. Dawson، نويسنده , , Suneel Gaur، نويسنده , , John Spencer، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    3297
  • To page
    3300
  • Abstract
    Water soluble prodrugs of hybrid free radical scavenger/iron chelating molecules, based on 3,5-disubstituted-4-hydroxyphenyl derivatives and 3-hydroxy-2-methyl-4(1H)-pyridinone (deferiprone), have been prepared. Related hybrid molecules containing a covalent poly(ethylene)glycol or an amine linker were also synthesized.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2002
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    792654