• Title of article

    Chemical modification of reveromycin A and its biological activities

  • Author/Authors

    Takeshi Shimizu، نويسنده , , Takeo Usui، نويسنده , , Kiyotaka Machida، نويسنده , , Kouichi Furuya، نويسنده , , Hiroyuki Osada، نويسنده , , Tadashi Nakata، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    3363
  • To page
    3366
  • Abstract
    Various derivatives of reveromycin A, a novel inhibitor of eukaryotic cell growth, were prepared and their inhibitory effects on both isoleucyl-tRNA synthetase activity and in vitro protein synthesis, and activities on the morphological reversion of srcts-NRK cells were assayed. The C5 hydroxyl group and C24 carboxyl group are particularly important for these activities.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2002
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    792670

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=792670