Title of article
Novel 2,5-dideoxystreptamine derivatives targeting the ribosomal decoding site RNA
Author/Authors
Dionisios Vourloumis، نويسنده , , Masayuki Takahashi، نويسنده , , Geoffrey C. Winters، نويسنده , , Klaus B. Simonsen، نويسنده , , Benjamin K. Ayida، نويسنده , , Sofia Barluenga، نويسنده , , Seema Qamar، نويسنده , , Sarah Shandrick، نويسنده , , Qiang Zhao، نويسنده , , Thomas Hermann، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
6
From page
3367
To page
3372
Abstract
The ribosomal decoding site is the target of aminoglycoside antibiotics that specifically recognize an internal loop RNA structure. We synthesized RNA-targeted 2,5-dideoxystreptamine-4-amides in which a sugar moiety in natural aminoglycosides is replaced by heterocycles.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792671
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