Author/Authors :
Neelam Bharti، نويسنده , , Kakul Husain، نويسنده , , M. T. Gonzalez Garza، نويسنده , , Delia E. Cruz-Vega، نويسنده , , J. Castro Garza، نويسنده , , Benito D. Mata-Cardenas، نويسنده , , Fehmida Naqvi، نويسنده , , Amir Azam، نويسنده ,
Abstract :
Several thiosemicarbazone derivatives of 5-nitrothiophene-2-carboxaldehyde were prepared by the simple process in which N4-thiosemicarbazone moiety was replaced by aliphatic, arylic and cyclic amine. Among these thiosemicarbazones compound 11 showed significant antiamoebic activity whereas compound 3 was more active antitrichomonal than the reference drug.
