Title of article :
A new series of potent benzodiazepine γ-secretase inhibitors
Author/Authors :
Ian Churcher، نويسنده , , Kate Ashton، نويسنده , , John W. Butcher، نويسنده , , Earl E. Clarke، نويسنده , , Timothy Harrison، نويسنده , , Huw D. Lewis، نويسنده , , Andrew P. Owens، نويسنده , , Martin R. Teall، نويسنده , , Susie Williams، نويسنده , , Jonathan D. J. Wrigley، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Pages :
5
From page :
179
To page :
183
Abstract :
A new series of benzodiazepine-containing γ-secretase inhibitors with potential use in the treatment of Alzheimerʹs disease is disclosed. Structure–activity relationships of the pendant hydrocinnamate side-chain which led to the preparation of highly potent inhibitors are described.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2003
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
792886
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=792886
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