Title of article
Synthesis of non-Natural C2-Homo-ceramide and its apoptotic activity against HL-60 cells
Author/Authors
Keiji Shikata، نويسنده , , Hayato Niiro، نويسنده , , Hideki Azuma، نويسنده , , Taro Tachibana، نويسنده , , Kenji Ogino، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
613
To page
616
Abstract
Non-natural ceramide analogues, C2-homo-ceramide and C2-homo-dihydroceramide, were prepared from -aspartic acid via -homo-serine. The apoptotic activities of the synthesized ceramide analogues were examined in HL-60 human leukemia cells. C2-homo- and C2-bishomo-ceramide indicate low but considerable apoptotic activities in comparison with C2-ceramide.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792977
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