Title of article
Docking studies of sulphamate inhibitors of estrone sulphatase in human carbonic anhydrase II
Author/Authors
Nigel Vicker، نويسنده , , Yaikat Ho، نويسنده , , James Robinson، نويسنده , , Lawrence L. W. Woo، نويسنده , , Atul Purohit، نويسنده , , Michael J. Reed، نويسنده , , Barry V. L. Potter، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
863
To page
865
Abstract
We describe the docking of selected steroidal and non-steroidal estrone sulphatase inhibitors, including the Phase I clinical trial candidate 667COUMATE (6), into the active site of human carbonic anhydrase II (hCA II). The docking scores are compared with the inhibition of hCA II and show good correlation with biological activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793033
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