Title of article
Synthesis of aza and oxaglutamyl-p-nitroanilide derivatives and Their kinetic studies with γ-Glutamyltranspeptidase
Author/Authors
Christian Lherbet، نويسنده , , Mylène Morin، نويسنده , , Roselyne Castonguay and، نويسنده , , Jeffrey W. Keillor، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
997
To page
1000
Abstract
A new series of -glutamic acid p-nitroanilide analogues has been synthesized and tested as substrates and inhibitors of rat kidney γ-glutamyltranspeptidase (GGT). Kinetic parameters (Km and kcat) were determined for each analogue and provide insight into the scope and limits of GGT catalytic efficiency.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793060
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