Title of article
Identification of a novel series of selective 5-HT7 receptor antagonists
Author/Authors
Ian T. Forbes، نويسنده , , David G. Cooper، نويسنده , , Emma K. Dodds، نويسنده , , Sara E. Douglas، نويسنده , , Andrew D. Gribble، نويسنده , , Robert J. Ife، نويسنده , , Andrew P. Lightfoot، نويسنده , , Malcolm Meeson، نويسنده , , Lorraine P. Campbell، نويسنده , , Tanya Coleman، نويسنده , , Graham J. Riley، نويسنده , , David R. Thomas، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
1055
To page
1058
Abstract
Novel 5-HT7 receptor antagonists containing the benzocycloheptanone core were identified from high throughput screening. Molecular modelling and SAR studies have converted these intractable hits into a more potent, selective and tractable series, exemplified by compound (25), SB-691673.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793073
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