Author/Authors :
Imre Schlemminger، نويسنده , , David R. Mole، نويسنده , , Luke A. McNeill، نويسنده , , Anupma Dhanda، نويسنده , , Kirsty S. Hewitson، نويسنده , , Ya Min Tian، نويسنده , , Peter J. Ratcliffe، نويسنده , , Christopher W. Pugh، نويسنده , , Andrea G. Prescott and Christopher J. Schofield، نويسنده ,
Abstract :
Analogues of the naturally occurring cyclic hydroxamate dealanylalahopcin, which is an inhibitor of procollagen prolyl-4-hydroxylase, were synthesised and shown to be inhibitors of the human hypoxia-inducible factor prolyl hydroxylases.