Author/Authors :
Stefan Jaroch، نويسنده , , Peter H?lscher، نويسنده , , Hartmut Rehwinkel، نويسنده , , Detlev Sülzle، نويسنده , , Gerardine Burton، نويسنده , , Margrit Hillmann، نويسنده , , Fiona M. McDonald، نويسنده ,
Abstract :
Dihydroquinolines with aminoalkyl side chains have been synthesized and have been shown to be potent n-NOS inhibitors. A marked selectivity versus e-NOS of up to approximately 300-fold was observed, whereas i-NOS was moderately inhibited.
