Title of article
Novel Inhibitors of Procollagen C-Terminal Proteinase. Part 1: Diamino Acid Hydroxamates
Author/Authors
N. G. J. Delaet، نويسنده , , L. A. Robinson، نويسنده , , D. M. Wilson، نويسنده , , R. W. Sullivan، نويسنده , , E. K. Bradley، نويسنده , , S. M. Dankwardt، نويسنده , , R. L. Martin، نويسنده , , H. E. Van Wart، نويسنده , , K. A. M. Walker، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
2101
To page
2104
Abstract
The parallel synthesis of novel inhibitors of procollagen C-terminal proteinase is described. The synthetic strategy allowed for the facile synthesis of a large number of side-chain diversified diamino acid hydroxamates, of which the -diaminopropionic acid derivatives were shown to be single digit nanomolar PCP inhibitors.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793305
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