Title of article
Synthesis and antimicrobial activity of novel globomycin analogues
Author/Authors
Toshihiro Kiho، نويسنده , , Mizuka Nakayama، نويسنده , , Kayo Yasuda، نويسنده , , Shunichi Miyakoshi، نويسنده , , Masatoshi Inukai، نويسنده , , Hiroshi Kogen، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
2315
To page
2318
Abstract
Globomycin, a signal peptidase II inhibitor, and its derivatives show potent antibacterial activity against Gram-negative bacteria. The synthesis and antimicrobial activity of novel globomycin analogues are reported. One of the analogues showed a more potent activity against Gram-negative bacteria than globomycin and also exhibited antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793347
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