Title of article :
4-Phenyl-4H-pyrans as IKCa channel blockers
Author/Authors :
Klaus Urbahns، نويسنده , , Ervin Horv?th، نويسنده , , Johannes-Peter Stasch، نويسنده , , Frank Mauler، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Abstract :
4-Phenyl-4H-pyrans have been identified as potent and specific IKCa channel blockers. Their synthesis and structure–activity relationships are described. A selected derivative, rac-11, reduces the infarct volume in a rat subdural hematoma model of traumatic brain injury after iv administration.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
