• Title of article

    4-Phenyl-4H-pyrans as IKCa channel blockers

  • Author/Authors

    Klaus Urbahns، نويسنده , , Ervin Horv?th، نويسنده , , Johannes-Peter Stasch، نويسنده , , Frank Mauler، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2003
  • Pages
    3
  • From page
    2637
  • To page
    2639
  • Abstract
    4-Phenyl-4H-pyrans have been identified as potent and specific IKCa channel blockers. Their synthesis and structure–activity relationships are described. A selected derivative, rac-11, reduces the infarct volume in a rat subdural hematoma model of traumatic brain injury after iv administration.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2003
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    793416