• Title of article

    Suzuki cross-coupling approaches to the synthesis of bioactive 3-substituted and 5-substituted-4-methoxy-6-methyl-2-pyrones

  • Author/Authors

    Lester R. Marrison، نويسنده , , Julia M. Dickinson، نويسنده , , Ian J. S. Fairlamb، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2003
  • Pages
    5
  • From page
    2667
  • To page
    2671
  • Abstract
    Suzuki cross-coupling has been used to access a wide range of 3- and 5-substituted 2-pyrones, which show remarkable inhibitory activity against bacteria, yeasts and fungi. 3-Octenyl and 5-octenyl 2-pyrones inhibit human ovarium carcinoma (A2780) and human chronic myelogenous leukaemia (K562) cell lines at the micromolar level.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2003
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    793423