Title of article
Design, synthesis and evaluation of novel azasugar-based MMP/ADAM inhibitors
Author/Authors
Hideki Moriyama، نويسنده , , Takahiro Tsukida، نويسنده , , Yoshimasa Inoue، نويسنده , , Hirosato Kondo، نويسنده , , Kohichiro Yoshino، نويسنده , , Shin-ichiro Nishimura، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
2741
To page
2744
Abstract
In order to verify whether azasugar would be a useful scaffold for inhibitory activity against metalloproteinases, we synthesized some azasugar-based compounds. As a result, it is clarified that azasugar moiety could function as successful inhibitor of matrix metalloproteinase-1, -3 and -9 and TACE.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793438
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