Title of article
Synthesis and antimycobacterial activity of capuramycin analogues. Part 1: substitution of the azepan-2-one moiety of capuramycin
Author/Authors
Hitoshi Hotoda، نويسنده , , Miyuki Furukawa، نويسنده , , Makiko Daigo، نويسنده , , Kazuhiro Murayama، نويسنده , , Masakatsu Kaneko، نويسنده , , Yasunori Muramatsu، نويسنده , , Michiko Miyazawa Ishii، نويسنده , , Shunichi Miyakoshi، نويسنده , , Toshio Takatsu، نويسنده , , Masatoshi Inukai، نويسنده , , Masayo Kakuta، نويسنده , , Tomomi Abe، نويسنده , , Tamako Harasaki، نويسنده , , Takashi Fukuoka، نويسنده , , Yukio Utsui، نويسنده , , Satoshi Ohya، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
2829
To page
2832
Abstract
Capuramycin analogues with a variety of substituents in place of the azepan-2-one moiety were synthesized from A-500359E and were tested for their translocase I inhibitory activity and in vitro antimycobacterial activity. Phenyl-type moieties were found to be effective substituents for capuramycin analogues.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793457
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