• Title of article

    MMPs inhibitors: new succinylhydroxamates with selective inhibition of MMP-2 over MMP-3

  • Author/Authors

    Valérie Marcq، نويسنده , , Catherine Mirand، نويسنده , , Martine Decarme، نويسنده , , Hervé Emonard، نويسنده , , William Hornebeck، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2003
  • Pages
    4
  • From page
    2843
  • To page
    2846
  • Abstract
    Some ilomastat analogues featuring an isobutylidene group or a 2-substituted indole nucleus were synthesized to evaluate their inhibitory activities against gelatinase A and stromelysin-1. Potent MMP-2 inhibition and good selectivity for that enzyme have been observed for compounds 1a, 2 and 22.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2003
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    793460

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=793460