Title of article :
Synthesis of pyrimidinopyridine–triazene conjugates targeted to abl tyrosine kinase
Author/Authors :
Zakaria Rachid، نويسنده , , Athanasia Katsoulas، نويسنده , , Fouad Brahimi، نويسنده , , Bertrand Jacques Jean-Claude، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Abstract :
The synthesis and abl tyrosine kinase inhibitory activities of alkyltriazenes conjugated to phenylaminopyrimidines are described. Significant abl inhibitory activities were observed only when a benzamido spacer was inserted between the 1,2,3-triazene chain and the 2-phenyaminopyridopyrimidine moiety.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
