Title of article
Ureas of 5-aminopyrazole and 2-aminothiazole inhibit growth of gram-positive bacteria
Author/Authors
John L. Kane Jr.، نويسنده , , Bradford H. Hirth، نويسنده , , Beirong Liang، نويسنده , , Brian B. Gourlie، نويسنده , , Sharon Nahill، نويسنده , , Gary Barsomian، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
4463
To page
4466
Abstract
Ureas of 5-aminopyrazole and 2-aminothiazole emerged as lead compounds from a high-throughput screen assaying the growth of Staphylococcus aureus. Structure–activity relationships were developed for each compound series. Several compounds were also tested for activity against drug resistant strains of S. aureus in vivo.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793802
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