Title of article
Pyridazines. Part 36: Synthesis and antiplatelet activity of 5-substituted-6-phenyl-3(2H)-pyridazinones
Author/Authors
Alberto Coelho، نويسنده , , Eddy Sotelo، نويسنده , , Nuria Fraiz، نويسنده , , Matilde Y??ez، نويسنده , , Reyes Laguna، نويسنده , , Ernesto Cano، نويسنده , , Enrique Ravi?a، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
321
To page
324
Abstract
A convenient and efficient palladium-catalysed retro-ene-assisted method has been developed to prepare a series of 5-substituted-6-phenyl-3(2H)-pyridazinones as potential antiplatelet drugs. The most active compounds were those that contain a 3-phenyl-3-oxo-propenyl fragment or a phenylthio group at position 5 of the heterocyclic ring.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793977
Link To Document