Title of article
Synthesis and pharmacological evaluation of prenylated and benzylated pterocarpans against snake venom
Author/Authors
Alcides J.M. da Silva، نويسنده , , Antonio L. Coelho، نويسنده , , Alessandro B.C. Simas، نويسنده , , Raphael A.M. Moraes، نويسنده , , Diogo A. Pinheiro، نويسنده , , Fabr??cio F.A. Fernandes، نويسنده , , Emerson Z. Arruda، نويسنده , , Paulo R.R. Costa، نويسنده , , Paulo A. Melo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
431
To page
435
Abstract
Edunol (3), a pterocarpan isolated from Harpalyce brasiliana, a plant used in the northeast of Brazil against snakebites, was obtained by synthesis and showed antimyotoxic, antiproteolytic and PLA2 inhibitor properties. These proprieties could be improved through the synthesis of a bioisoster (5), where the prenyl group was replaced by the benzyl group.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794002
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