Title of article
Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738
Author/Authors
Masae Sawada، نويسنده , , Ken-ichi Washizuka، نويسنده , , Hiroyuki Okumura، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
633
To page
637
Abstract
The synthesis and biological properties of a novel squalene epoxidase inhibitor, FR194738, are described. This compound displayed potent in vitro inhibitory activities against squalene epoxidase and cholesterol synthesis, and lowered plasma cholesterol and triglyceride levels in dogs.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794044
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