• Title of article

    Studies on 1-O-acetylbritannilactone and its derivative, (2-O-butyloxime-3-phenyl)-propionyl-1-O-acetylbritannilactone ester

  • Author/Authors

    Shouxin Liu، نويسنده , , He Liu، نويسنده , , Weiying Yan، نويسنده , , Li Zhang، نويسنده , , Naisheng Bai، نويسنده , , Chi-Tang Ho، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2004
  • Pages
    4
  • From page
    1101
  • To page
    1104
  • Abstract
    The crystal structures of 1-O-acetylbritannilactone 6 isolated from Inula britannica, and its derivative (2-O-butyloxime-3-phenyl) propionyl 1-O-acetylbritannilactone ester 7 are reported. The structure of synthesized derivative 7 was established by spectroscopic methods. Both compounds inhibited the growth of human HL-60, Bel-7402 cell lines and compound 7 had the stronger cytotoxic activity.
  • Keywords
    Inula britannica , Sesquiterpene lactone , cytotoxicity , (2-Obutyloxime-1-phenyl) propionic acid derivative , X-ray crystal structures.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2004
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    794139