Title of article
Syntheses and biological evaluation of new fluoroquinolone antibacterials containing chiral oxiimino pyrrolidine
Author/Authors
Dong-Rack Choi، نويسنده , , Jung-Han Shin، نويسنده , , Jin Yang، نويسنده , , Sue Hye Yoon، نويسنده , , Yong Ho Jung، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
1273
To page
1277
Abstract
The design and syntheses of new fluoroquinolone antibacterial agents having pyrrolidine ring at C-7 position are described. The pyrrolidine ring is optically active and possesses methyloxime functional group. Two of them have excellent in vitro antibacterial activities and pharmacokinetic profiles.
Keywords
Antibacterial activity , flu oroquinolone , fax: +82-3144-69556 , oxiimino pyrrolidine.* Corresponding author. Tel.: +82-3144-52485 , e-mail: org301@iris.dwcrc.co.kr
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794175
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