A series of heterocyclic inhibitors of phenylalanyl-tRNA synthetases with antibacterial activity
Author/Authors :
Xiang Y. Yu، نويسنده , , John Finn، نويسنده , , Jason M. Hill، نويسنده , , Zhong G. Wang، نويسنده , , Dennis Keith، نويسنده , , Jared Silverman، نويسنده , , N. Oliver، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Pages :
4
From page :
1343
To page :
1346
Abstract :
A series of novel heterocyclic analogues have been synthesized and evaluated for their ability to inhibit phenylalanyl-t-RNA synthetases and act as antibacterial agents. Several analogues have good antibacterial activity against Staphylococcus aureus.