Author/Authors :
L.S.M Miranda، نويسنده , , Bruno G Marinho، نويسنده , , Suzana G Leit?o، نويسنده , , Maria Eline Matheus، نويسنده , , Patr??cia D Fernandes، نويسنده , , M.L.A.A Vasconcellos، نويسنده ,
Abstract :
We described in this paper the first synthesis to the (±) cis (6-ethyl-tetrahydropyran-2-yl) formic acid (1) using the very efficient Prins cyclization reaction as strategy to construction of its tetrahydropyran skeleton. This new compound presented a significant antinociceptive property by the tail-flick model.
