Title of article
(±)-cis-(6-Ethyl-tetrahydropyran-2-yl)-formic acid: a novel substance with antinociceptive properties
Author/Authors
L.S.M Miranda، نويسنده , , Bruno G Marinho، نويسنده , , Suzana G Leit?o، نويسنده , , Maria Eline Matheus، نويسنده , , Patr??cia D Fernandes، نويسنده , , M.L.A.A Vasconcellos، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
3
From page
1573
To page
1575
Abstract
We described in this paper the first synthesis to the (±) cis (6-ethyl-tetrahydropyran-2-yl) formic acid (1) using the very efficient Prins cyclization reaction as strategy to construction of its tetrahydropyran skeleton. This new compound presented a significant antinociceptive property by the tail-flick model.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794237
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