Title of article
Synthesis of potent sigma-1 receptor ligands via fragmentation of dextromethorphan
Author/Authors
Mark P. Arrington، نويسنده , , Claire Brown، نويسنده , , C.Eric Schwartz، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
3
From page
1807
To page
1809
Abstract
Treatment of dextromethorphan 1 with various alkylating agents followed by base treatment led to Hoffman-type elimination reactions to produce a series of tricyclic derivatives, 6. These derivatives were characterized in vitro as sigma-1 receptor ligands.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794287
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