Author/Authors :
Mankil Jung، نويسنده , , Kyunghoon Lee، نويسنده , , Hochul Jung، نويسنده , , Howard Kendrick، نويسنده , , Vanessa Yardley، نويسنده , , Simon L. Croft، نويسنده ,
Abstract :
(+)-Deoxoartemisitene and its C-11, 13 derivatives were synthesized from artemisinic acid via a short and regiospecific process and several derivatives show 10–20 times more in vitro antimalarial activities against Plasmodium falciparum than artemisinin.