Title of article
Biaryl amide glucagon receptor antagonists
Author/Authors
Ravi Kurukulasuriya، نويسنده , , Bryan K. Sorensen، نويسنده , , James T. Link، نويسنده , , Jyoti R Patel، نويسنده , , Hwan-Soo Jae، نويسنده , , Marty X Winn، نويسنده , , Jeffrey R Rohde، نويسنده , , Nelson D Grihalde، نويسنده , , Chun W Lin، نويسنده , , Christopher A Ogiela، نويسنده , , Andrew L Adler، نويسنده , , Christine A Collins، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
2047
To page
2050
Abstract
Biaryl amides derived from a reported series of ureas 1 were evaluated and found to be potent human glucagon receptor antagonists. The benzofuran analogue 6i was administered in Sprague–Dawley rats and blocked the effects of an exogenous glucagon challenge.
Keywords
Hepatic glucose productioninhibitors. , Glucagon receptor antagonist
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794335
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