Title of article
Synthesis and antitumor evaluation of benzoylphenylurea analogs
Author/Authors
Hallur Gurulingappa، نويسنده , , Maria L Amador، نويسنده , , Ming Zhao، نويسنده , , Michelle A Rudek، نويسنده , , Manuel Hidalgo، نويسنده , , Saeed R Khan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
2213
To page
2216
Abstract
Novel series of benzoylphenylurea analogs 7–10 were prepared and evaluated for in vitro cytotoxic activity against a panel of eight different human cancer cell lines. A very interesting inhibition profile against BxPC3, Mia-Paca, and Hep2 cells with compound 10 has been observed. Compounds 8 and 9 showed the significant cytotoxicity in Hep2 cells. All cell lines were resistant to compound 7.
Keywords
Benzoylphenylurea analogs , Antitumor agents.* Corresponding author. Tel.: +1-410-614-0200 , fax: +1-410-614-8397 , e-mail: khansa@jhmi.edu
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794370
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