Title of article :
Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides
Author/Authors :
Xenia Beebe، نويسنده , , Fan Yang، نويسنده , , Mai H. Bui، نويسنده , , Michael J. Mitten، نويسنده , , Zhenkun Ma، نويسنده , , Angela M. Nilius، نويسنده , , Stevan W. Djuric، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
A series of novel 6-O-arylpropargyl-9-oxime-ketolides was synthesized and evaluated against various pathogens. These new compounds show promising in vitro antibacterial potency and in vivo efficacy against macrolide resistant strains.
Keywords :
Macrolides , Antibacterial.* Corresponding author. Tel.: +1-847-937-8291 , e-mail: xenia.b.searle@abbott.com , fax: +1-847-935-0310 , ketolides
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
