Title of article :
The effect of C2-fluoro group on the biological activity of DC-81 and its dimers
Author/Authors :
Ahmed Kamal، نويسنده , , P. S. M. M. Reddy، نويسنده , , D. Rajasekhar Reddy، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
C2-Fluoro substituted pyrrolobenzodiazepines (PBDs) have been synthesized that exhibit potential anticancer activity in a number of human tumour cell lines. These C2-fluoro substituted PBDs also exhibit significant DNA-binding ability.
Keywords :
Cytotoxicity and DNAbindingaffinity. , C2-Fluoropyrrolobenzodiazepines
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
