Author/Authors :
Ichiro Suzuki، نويسنده , , Shinsaku Uno، نويسنده , , Yuko Tsuchiya، نويسنده , , Akira Shigenaga، نويسنده , , Hisao Nemoto، نويسنده , , Masayuki Shibuya، نويسنده ,
Abstract :
Enediyne model compounds possessing photo-triggering devices were developed. These enediynes afforded biradicals by UV irradiation and showed DNA cleaving activity. The DNA damage was confirmed to be mainly caused by the biradical, not singlet oxygen.
