Author/Authors :
Graham B. Jones، نويسنده , , Longfei Xie، نويسنده , , Ahmed El-Shafey، نويسنده , , Curtis F. Crasto، نويسنده , , Glenn J. Bubley، نويسنده , , Anthony V. D’Amico، نويسنده ,
Abstract :
A family of image contrast agent conjugates designed to undergo enzymatic activation has been synthesized. The agents underwent activation both with enzymatically active prostate specific antigen and α-chymotrypsin, releasing free fluorophore via cleavage of a three-component system.